Flow Cytometry

Flow Cytometry

Unparalleled in identifying the presence and populations of various cells in blood and bone marrow, flow cytometry is based on the principle of a stream of single cells passing before a set of lasers that discreetly detect, sort, and count them.

Antibodies (markers) attached to proteins expressed by the cells then allow hematopathologists to see population patterns associated with malignancy or disruption of cell cycles and regulation.

Service Attributes

  • 24 hour turnaround time
  • State-of-the-art 10-color technology
  • Quantitative reporting with representative scatter plots
  • Disease-focused panels* for myeloid, lymphoid, plasmacytic, and mast cell disorders
  • MRD testing for ALL, AML, CLL, and myeloma
  • Ultrasensitive FLAER PNH testing (0.01%), consistent with International Clinical Cytometry Society (ICCS) guidelines
  • Global and TC-only services
Flow Cytometry
Add-On Panels
Markers
AML Add-On Panel cCD3, cCD13, CD13, CD19, cCD22, CD33, CD34, CD41, CD45, CD61, cCD79a, cMPO, nTdT
B-ALL Add-On Panel CD10, CD19, CD20, CD22, CD33, CD34, CD38, CD45, CD58, CD123, cIgM
CLL Prognostication Add-On Panel CD5, CD19, CD45, CD49d, CD52, CD56, ZAP-70
Follicular / Large B-Cell Lymphoma Add-On Panel BCL2, CD10, CD19, CD45
Hairy Cell Leukemia Add-On Panel CD11c, CD19, CD25, CD45, CD103, CD123
Limited Myeloid Screen Panel CD13, CD14, CD16, CD19, CD33, CD34, CD45, CD117, HLA-DR
Mast Cell Panel CD2, CD25, CD45, CD117
T-ALL Add On Panel CD1a, CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD34, CD45
Flow Cytometry Panels Markers
AML Panel CD2, CD3, CD4, CD7, CD8, CD10, CD11b, CD13, CD14, CD15, CD16, CD19, CD33, CD34, CD36, CD38, CD45, CD56, CD64, CD65, CD71, CD105, CD117, CD123, CD235a, HLA-DR, Kappa, Lambda, nTdT, cMPO, cCD3, cCD13, cCD22, cCD79a, CD41, CD61
Lymphocyte Subset Panel CD3, CD4, CD8, CD19, CD45, CD56
Lymphoma Standard Panel CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD16, CD19, CD20, CD23, CD38, CD43, CD45, CD56, CD57, CD79b, CD103, CD123, CD200, Kappa, Lambda
Lymphoplasmacytic Lymphoma Panel (LPL) CD3, CD4, CD5, CD8, CD10, CD19, CD20, CD23, CD27, CD28, CD38, CD45, CD56, CD79b, CD81, CD117, CD138, IgA, IgG, IgM, surface Kappa, surface Lambda, cytoplasmic Kappa, cytoplasmic Lambda
Lymphoproliferative Disorders Panel (LPD) CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD16, CD19, CD20, CD23, CD38, CD43, CD45, CD56, CD57, CD79b, CD103, CD123, CD200, Kappa, Lambda
Myelodysplastic Syndrome Panel (MDS) CD2, CD3, CD4, CD7, CD8, CD10, CD11b, CD13, CD14, CD15, CD16, CD19, CD33, CD34, CD36, CD38, CD45, CD56, CD64, CD65, CD71, CD105, CD117, CD123, CD235a, HLA-DR, Kappa, Lambda
Myeloproliferative Disorders Panel (MPD) CD3, CD4, CD5, CD8, CD14, CD19, CD20, CD33, CD34, CD38, CD45, CD56, Kappa, Lambda
Myeloma Panel CD3, CD4, CD8, CD19, CD20, CD27, CD28, CD38, CD45, CD56, CD81, CD117, CD138, IgA, IgG, IgM, cKappa, cLambda
Pancytopenia Panel CD2, CD3, CD4, CD5, CD7, CD8, CD14, CD16, CD19, CD20, CD33, CD34, CD38, CD45, CD56, CD57, CD103, CD123, Kappa, Lambda, TCR gamma/delta
Paroxysomal Nocturnal Hemoglobinuria (PNH) Panel
(Meets International Clinical Cytometry Society guidelines)
CD14, CD15, CD24, CD33, CD45, CD59, CD235a, FLAER
T/NK-Cell Lymphoma Panel CD2, CD3, CD4, CD5, CD7, CD8, CD16, CD19, CD38, CD45, CD56, CD57, Kappa, Lambda, TCR gamma/delta

"My expectations are constantly exceeded by the turnaround time, personalized service, and collaborative approach to reach the correct diagnosis."

Desiree A. Carlson, MD
Chief of Pathology, Signature Healthcare

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A Model Experience

With core values rooted in service and integrity, our leadership team sets the bar high.

We consistently strive to set the model for exactly how a reference laboratory should engage with both physicians and patients.

Patient-Friendly Billing

All billing is treated as in-network regardless of insurance company.

Patients are only responsible for payments according to their in-network benefit program, co-insurance and/or deductible for laboratory services.

Accredited and Certified

siParadigm is accredited by CLIA (Clinical Laboratory Improvement Amendments) and certified by CAP (College of American Pathologists).

We also hold select state licensure where required.