Morphology / IHC

Morphology/IHC

While molecular and sequencing techniques continue to evolve and uncover new aspects of disease, morphology remains the basis for our understanding of the inherent nature of cells and their architecture when viewed under a microscope.

Immunohistochemistry (IHC) and special stains, give contrast to mark cell features and expressed proteins that uncover staining patterns (algorithms) to characterize and diagnose blood and solid tumor cancers.

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Immunohistochemistry (IHC) Antibodies

Actin (muscle specific) / HHF35
Actin (smooth muscle) (SMA)
ALK-1
Alpha-1 Fetoprotein (AFP)
Annexin-A1
Amyloid
Arginase-1
B72.3 (TAG 72)
BCL-1 (Cyclin-D1)
BCL-2
BCL-6
Ber EP4
Beta HCG
Bg8
BOB1
Breast Cocktail
CA-125
CA19.9
Caldesmon
Calponin
Calretinin
CAM5.2 (CK8/18/19) (LMCK)
CD1a
CD2
CD3
CD4
CD5
CD7
CD8
CD10
CD15
CD20
CD21
CD23
CD30
CD31
CD34
CD43
CD45 (LCA)
CD56
CD57
CD61
CD68
CD71
CD79a
CD99
CD117 (C-KIT)
CD138
CD138 / Ki-67
CDX2
CEA (Monoclonal)
CEA (Polyclonal)
Chromogranin A
CK5/6
CK7
CK17
CK19
CK20
CK903 (HMCK)
CMV
C-MYC
D2-40
Desmin
E-Cadherin
ER
Factor VIII (vW)
Factor XIIIa
Fascin
GATA3
GCDFP-15
GFAP
GLUT1
Glycophorin A (CD235)
Glypican 3
Granzyme B
H. pylori
HBME-1
HepPar 1
HER2 /neu
HHV8
HMB45
HNF1β
HSV-1
HSV-2
IgA
IgG
IgG4
IgM
Inhibin
Kappa
Ki-67 (MIB-1)
Lambda
Lysozyme
Mammoglobin
Melan A (MART-1)
MiTF-1
MLH1
MOC-31
MSH2
MSH6
MUM1
MPO
Napsin-A
NSE
OCT2
OCT4
p16
p40
p504S
p53
p57
p63
p120 Catenin
PAX-5
PAX-8
PCK AE1/AE3 (Pan)
PD-1
PDL-1 22C3
PIN4
PLAP
PMS2
PR
PSA
PSAP
PSMA
RCC
S-100
SMMS-1
SOX10
SOX11
Synaptophysin
TdT
Thrombomodulin
Thyroglobulin
TIA-1
TRAcp
TTF-1
Tyrosinase
Uroplakin II
Vimentin
WT-1
ZAP-70
IHC Panels
Breast Panel ER, PR, HER2, Ki67
Lymphoma Panel BCL-1, BCL-2, BCL-6, CD3, CD5, CD10, CD20, CD21, CD23, CD43, Ki-67
Melanoma Panel S-100, Melan A, Tyrosinase
Mismatch Repair (MMR) Panel MLH1, MSH2, MSH6, PMS2
Myeloma Panel CD56, CD138, IgA, IgG, IgM, Kappa, Lambda
Neuroendocrine Panel CD56, Chromogranin A, NSE, Synaptophysin

Special Stains

AFB
Congo Red
H&E
Pap
Reticulin
Alcian Blue
Giemsa
Iron
PAS
Trichrome
Alcian Blue/PAS
GMS
Mucicarmine
PAS (Fungus)
Wright Giemsa

In Situ Hybridization (ISH)

EBER
HPV-HR
HPV-LR
Kappa
Lambda

"My expectations are constantly exceeded by the turnaround time, personalized service, and collaborative approach to reach the correct diagnosis."

Desiree A. Carlson, MD
Chief of Pathology, Signature Healthcare

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With core values rooted in service and integrity, our leadership team sets the bar high.

We consistently strive to set the model for exactly how a reference laboratory should engage with both physicians and patients.

Patient-Friendly Billing

All billing is treated as in-network regardless of insurance company.

Patients are only responsible for payments according to their in-network benefit program, co-insurance and/or deductible for laboratory services.

Accredited and Certified

siParadigm is accredited by CLIA (Clinical Laboratory Improvement Amendments) and certified by CAP (College of American Pathologists).

We also hold select state licensure where required.