Morphology / IHC

Morphology/IHC

Morphologic evaluation remains fundamental to the practice of diagnostic pathology in the routine clinical laboratory setting. siParadigm offers an extensive array of in house immunohistochemistry (IHC), in-situ hybridization (ISH), and special histologic stains. Global and technical only options are available.

Best-In-Class Service

  • 24 hour turnaround time
  • Global and Tech Only (TC) services
  • Including PD-L1 22C3 for Keytruda®

Immunohistochemistry (IHC) Antibodies

Actin (muscle specific)
Actin (smooth muscle)
ADH-5
AFB
ALK-1
ALK D5F3
Alpha-1 Fetoprotein
Amyloid-A
Annexin A1
Arginase
Alcian Blue
B72.3 / TAG-72
Bcl1
Bcl-2
Bcl-6
BerEP4
Beta HCG
Beta-Catenin
BRAF
Bg8
Bob.1
CA 125
CA19-9
Caldesmon
Calponin
Calretinin polyclonal
CAM 5.2/CK8&18
CD10
CD103
CD117
CD138
CD163
CD15
CD1a
CD2
CD20
CD21
CD23
CD3
CD30
CD31
CD34
CD4
CD43
CD45 (LCA)
CD5
CD56
CD57
CD61
CD68
CD7
CD71
CD79α
CD8
CD99
CDX2
CEA, polyclonal
CEA, monoclonal
Chromagranin A
CK17
CK19
CK20
CK 5/6
CK7
CK903
Congo Red
CMV
C-Myc
D2-40
Desmin
DOG-1
EBER
E-Cadherin
EMA
Estrogen Receptor
Fascin
Folate Receptor Alpha
FVIII (von Willebrand)
FXIIIa
GATA3
GCDFP-15
GFAP
GMS
GlycophorinA
Glypican-3
Granzyme B
H. pylori
HBME-1
Hepatocyte (HepPar1)
HER2-neu
HSV type II
HHV-8
HMB45
HNFI-1 BETA
HPV-6/11
HPV-16/18
HPV-31/33
HSV type I
IgA
IgG
IgG4
IgM
Inhibin
Kappa light chain
Kappa ISH
Ki-67
Lambda light chain
Lambda ISH
Lysozyme
Mammaglobin
Mucicarmine
MELAN-A
MiTF-1
MLH-1
MSH-2
MSH-6
MOC-31
MUM1
Myeloperoxidase
NSE
Napsin
2-Oct
4-Oct
PAS
P120 Catinin
P16
P40
P504s
P53
P57
P63
PAX-5
PIN-4
PLAP
PMS-2
PAX-8
PCK, AE1/AE3
PD-1
PD-L1 22C3
PD-L1 28-8
PD-L1 SP142
PD-L1 SP263
PR
PSA
PSAP
PSMA
RCC
Reticulum
S100, polyclonal
SMMS-1
SOX-10
SOX-11
STAT-6
Synaptophysin
TdT
Thrombomodulin
Thyroglobulin
TIA-1
TRAcp
Trichrome
TTF-1
Tyrosinase
Uroplakin
Vimentin
Wilms' Tumor 1 (WT1)
IHC Panels
Breast Panel ER, PR, HER2, Ki67
Lymphoma Panel BCL-1, BCL-2, BCL-6, CD3, CD5, CD10, CD20, CD21, CD23, CD43, Ki-67
Melanoma Panel S-100, Melan A, Tyrosinase
Mismatch Repair (MMR) Panel MLH1, MSH2, MSH6, PMS2
Myeloma Panel CD56, CD138, IgA, IgG, IgM, Kappa, Lambda
Neuroendocrine Panel CD56, Chromogranin A, NSE, Synaptophysin

Special Stains

AFB
Amyloid
Congo Red
H&E
Pap
Reticulin
Alcian Blue
Giemsa
Iron
PAS
Trichrome
Alcian Blue/PAS
GMS
Mucicarmine
PAS (Fungus)
ROS-1
Wright Giemsa

In Situ Hybridization (ISH)

EBER
HPV-HR
HPV-LR
Kappa
Lambda

"My expectations are constantly exceeded by the turnaround time, personalized service, and collaborative approach to reach the correct diagnosis."

Desiree A. Carlson, MD
Chief of Pathology, Signature Healthcare

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A Model Experience

With core values rooted in service and integrity, our leadership team sets the bar high.

We consistently strive to set the model for exactly how a reference laboratory should engage with both physicians and patients.

Accredited and Certified

siParadigm is accredited by CLIA (Clinical Laboratory Improvement Amendments) and certified by CAP (College of American Pathologists).

We also hold select state licensure where required.